TRX2 predominantly targets a specific type of potassium channels found within hair follicles (similar as minoxidil does). TRX2 works together with your metabolism to achieve particular metabolic changes, such as increased cardiolipin synthesis (important for optimization of the hair follicle cell membrane and therefore potassium channel activity), increased ATP synthesis (important as substrate for potassium channel translocation) and de-novo potassium channel synthesis (or reactivation of existing potassium channels by providing the compounds needed for synthesis and triggering (re-)assembly).

Unlike 5-alpha reductase inhibitors such as finasteride or dutasteride, which target the reduction of DHT on a hormonal level, TRX2 targets the reduction of DHT on a molecular level. The idea is to repair broken molecular mechanisms (i.e. potassium channel synthesis and activity) at first and therefore deduce/eliminate the damage DHT can do to the hair follicle at second.

Rather than treating hair loss symptomatically (i.e. treating hair loss once hormons are doing damage) TRX2 aims to address the more underlying, broken molecular strings, which have allowed DHT to damage the hair follicle at the first place.